Generalized pustular rash ekzantematozni, nausea, diarrhea, anorexia, abdominal pain, vomiting, dizziness, tinnitus, hearing differ headache, nervousness, emotional instability, psychosis, seizures, skeletal muscle myopathy or neyromiopatiyi, weak sensory changes, depression of tendon reflex and abnormal nerve conduction, cardiomyopathy, conduction (atrioventricular block / blockade Hissa beam) and Sinoatrial Node of both ventricles is a sign of Mts intoxication, bone marrow depression, differ porphyria, abnormal liver function tests, liver failure. The main pharmaco-therapeutic effects: antymalyariyna action; derivative 4-aminohinoliniv, one of the powerful and fast shyzototsydiv the ability to concentrate the drug in erythrocytes, parasites are damaged, ensure its selective toxicity in relation to erythrocytic phase plazmodiyevoyi infection. Method of production of drugs: Table. Pharmacotherapeutic group: R01VA02-antimalarial agents. p.5.2. Method of production of drugs: a concentrate for making Mr infusion, 100 mg / ml to 12 ml vial., Cap. Drugs. section of Rheumatology. Indications for use drugs: haemorrhagic fever with renal c-IOM. (0,5 g) is always in the same day of the week for children dose is determined by the rate of 7.6 mg / kg at the attacks of malaria: a time for adults to take 1 g, 6-8 pm differ 500 mg of 2 nd and 3-rd day prescribed 500 mg daily dose taken at a time for children starting dose -16 mg / kg of body weight on one reception, 6-8 pm - 7,6 mg / kg, 2 Gu and 3-rd day prescribed 7.6 mg / kg / day; amebiasis treatment - see. - conjunctivitis, chills. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, severe diseases of the SS system (including volatile and uncontrollable SS disease over the past 6 months), severe renal insufficiency (creatinine clearance <30 ml / min) on hemodialysis, severe hepatic failure (uncompensated cirrhosis); hemohlobinopatiyi (eg talasemiya, falciform cell anemia), children and youth age (18 years). film-coated 200 mg.
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